PREVALENCE OF UROPATHOGEN AND ANTIBIOTIC SUSCEPTIBILITY PROFILE OF UROPATHOGEN ISOLATED FROM URINE AT TERTIARY CARE HOSPITAL PESHAWAR

Abstract

Urinary tract infection (UTI) is one of serious health problem and should be address on urgent basis. It is one of important cause of prolong stay of patients in hospitals and economic burden on society. UTI primarily affects the Urinary tract; along other parts of body. This was descriptive crossectional study conducted at Khyber Teaching Hospital Peshawar, Pakistan design to determine the prevalence of Uropathogen in district Peshawar, Pakistan and to find out the antibiotic susceptibility profile of uropathogen. Total 131 Urine samples were collected from both male and females of all ages group who presents clinical sign and symptoms of urinary tract infection while antibiotic prophylaxis patients and patients who were unable to give sample excluded from the current study. Out of these 131 UTI patients there were 51 confirmed cases including 35 female and 21 males having mean age between 1-35 years were more effected as compared to other age group. AST profile showing that the most resistance antibiotic was Cefiod and most Sensetive antibiotic was amikacin against bacteria. From the current it was concluded the study showed that UTIs are the leading public-health problem mainly in women. In our study, the predominant isolated organisms responsible for UTI in Pakistan were E. coli, Citrobacter and Morganella. The majority of isolates were resistant to commonly prescribed antibiotics. Therefore, routine monitoring and surveillance are crucial for the better management of patients. 

Keywords : UTI, Antibiotic, AST, Prevalence, Sensetive, Resistance