COMPARATIVE ANALYSIS OF HEMODIALYSIS AND PERITONEAL DIALYSIS IN TERMS OF SURVIVAL RATE: A SYSTEMATIC REVIEW

Abstract

Background: End-stage renal disease is a major global health issue, and dialysis remains the primary treatment option for many patients. Hemodialysis and peritoneal dialysis are widely used modalities, but their comparative survival outcomes remain controversial. Objective: To compare survival outcomes between Hemodialysis and peritoneal dialysis in patients with End-stage renal disease using evidence from observational and cohort studies. Methodology: A systematic review was conducted using electronic databases including PubMed, Scopus, Google Scholar, and Cochrane Library. Studies published between 2020 and 2026 were selected based on predefined inclusion and exclusion criteria. Relevant data were extracted and analyzed qualitatively. Results: The findings showed that overall survival between Hemodialysis and peritoneal dialysis is comparable, with no significant difference in mortality. However, a time-dependent pattern was observed, where peritoneal dialysis demonstrated better early survival, while hemodialysis showed improved long-term outcomes. Patient characteristics and clinical factors significantly influenced survival. Conclusion: Both Hemodialysis and peritoneal dialysis are effective treatment options with similar overall survival. The choice of modality should be individualized based on patient condition and preferences.